Protective Effects of Sida Veronicaefolia against RIF+INH Induce Hepatotoxicity in Experimental Animals
نویسندگان
چکیده
In the current research, rats will be given RIF+INH (hepatotoxic), and hydoethanol (HEESV) extract of leaves Sida veronicaefolia tested to see how well it protects rats' livers from damage caused by RIF+INH. Liver function tests serum profiles were used provide an estimate hepatoprotective effects HEESV at a dose 500 mg/kg. According findings, extracts not only strong impact lowering blood levels transaminases (SGPT SGOT), alkaline phosphate, total bilirubin, but they also considerably enhance protein. The quite similar those standard medication silymarin.
منابع مشابه
Protective effects of Sida veronicaefolia against ethanol induced hepatotoxicity in experimental animals
The present study is to evaluate the hepatoprotective effects of the ethanol (EESV) and aqueous (AESV) extracts of leaves of Sida veronicaefolia, against ethanol induced hepatotoxicity in rats. The hepatoprotective effects of EESV (500 mg/kg) and AESV (500 mg/kg) were estimated by liver function test and serum profile. The results revealed that both the extracts of selected plant produce signif...
متن کاملProtective effects of Baccharis dracunculifolia leaves extract against carbon tetrachloride- and acetaminophen-induced hepatotoxicity in experimental animals.
In this work we investigated the in vivo protective effects of Baccharis dracunculifolia leaves extract (BdE) against carbon tetrachloride (CCl4)- and acetaminophen (APAP)-induced hepatotoxicity. Total phenolic content, total flavonoid content, antioxidant DPPH radical scavenging activity, and HPLC analysis were performed. Our results showed that pretreatment with BdE significantly reduced the ...
متن کاملAntitumor activity of Sida Veronicaefolia against Ehrlich Ascites Carcinoma in mice
The acetone and ethanol extracts from the leaves of Sida Veronicaefolia i.e. AESV and EESV respectively were evaluated for antitumor activity against Ehrlich Ascites Carcinoma (EAC) bearing Swiss albino mice. The extracts were administered at the doses of 500 mg/kg body weight per day for 14 days after 24 h of tumor inoculation. 24 h after the last dose, with fasting, the mice were sacrificed. ...
متن کاملProtective Effects of Propolis Against the Amitraz Hepatotoxicity in Mice
The present study aimed to study the protective effects of honeybee propolis against the amitraz hepatotoxicity in mice. Forty-eight Swiss albino male mice of 8 weeks of age, 22 to 25 g body weight were divided into four groups. The 1 was control, the 2 was treated orally with 150 mg kg propolis extract, the 3 was treated with 160 mg kg amitraz and the 4 one had 160 mg kg amitraz + 150 mg kg pr...
متن کاملThe protective effects of naringin against 5-fluorouracil-ınduced hepatotoxicity and nephrotoxicity in rats
Objective(s): 5-FU, an anticarcinogenic agent, is reported to have side-effects that include hepatotoxicity and nephrotoxicity. The study objective was to investigate the protective effects of naringin on 5-FU-induced hepatotoxicity and nephrotoxicity.Materials and Methods: Thirty rodents were assigned to three groups. The control group received 1 ml of intragastric distilled water for 14 days....
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Medical and Biomedical Studies
سال: 2022
ISSN: ['2589-868X', '2589-8698']
DOI: https://doi.org/10.32553/ijmbs.v6i11.2628